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Article

Polymorphic variation in NFKB1 and other aspirin-related genes and risk of Hodgkin lymphoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2009

Chang Ellen T, Birmann Brenda M, Kasperzyk Julie L, Conti David V, Kraft Peter, Ambinder Richard F, Zheng Tongzhang, Mueller Nancy E

Abstract excerpt

We found that regular use of aspirin may reduce the risk of Hodgkin lymphoma (HL), a common cancer of adolescents and young adults in the United States. To explore possible biological mechanisms underlying this association, we investigated whether polymorphic variation in genes involved in nuclear factor-kappaB (NF-kappaB) activation and inhibition, other inflammatory pathways, and aspirin metabolism influences...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19223558
DOI: 10.1158/1055-9965.EPI-08-1130
PMCID: PMC2720066

Genes

NFKB1
CHUK
NFKBIA
PTGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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