Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of Epithelial Branching Morphogenesis and Cancer Cell Growth of the Prostate by Wnt Signaling

13 May 2008

Abstract excerpt

Although Wnt signaling has been shown to be important for embryonic morphogenesis and cancer pathogenesis of several tissues, its role in prostatic development and tumorigenesis is not well understood. Here we show that Wnt signaling regulated prostatic epithelial branching morphogenesis and luminal epithelial cell differentiation in developing rat prostate organ cultures. Specifically, Wnt signaling regulated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Prostate Cancer Treatment and Research
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18478098
DOI: 10.1371/journal.pone.0002186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of Epithelial Branching Morphogenesis and Cancer Cell Growth of the Prostate by Wnt SignalingPMID 18478098Read ↗

Conserved Gene Expression Programs Integrate Mammalian Prostate Development and TumorigenesisSemantic proximity Read ↗

Wnt signaling and prostate cancer.Semantic proximity Read ↗

Exploring the Wnt Pathway as a Therapeutic Target for Prostate CancerSemantic proximity Read ↗

β-Catenin Is Required for Prostate Development and Cooperates with Pten Loss to Drive Invasive CarcinomaSemantic proximity Read ↗

WNT SIGNALING IN PROSTATE DEVELOPMENT AND CARCINOGENESISSemantic proximity Read ↗

Wnt activator FOXB2 drives the neuroendocrine differentiation of prostate cancerSemantic proximity Read ↗

Survey of genetically engineered mouse models for prostate cancer: Analyzing the molecular basis of prostate cancer development, progression, and metastasisSemantic proximity Read ↗

WNT5A Has Anti-Prostate Cancer Effects In Vitro and Reduces Tumor Growth in the Skeleton In VivoSemantic proximity Read ↗

TIAM1 drives prostatic branching phenotype and is a potential therapeutic target for benign prostatic hyperplasia.Semantic proximity Read ↗

Essential roles of epithelial bone morphogenetic protein signaling during prostatic development.Semantic proximity Read ↗

Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis.Semantic proximity Read ↗

Hormonal, cellular, and molecular control of prostatic development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.