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Article

A novel PAX3 rearrangement in embryonal rhabdomyosarcoma.

Cancer genetics and cytogenetics - 1 Mar 2009

Hosoi Hajime, Kakazu Naoki, Konishi Eiichi, Tsuchihashi Yasunari, Hada Satoshi, Amaya Eriko, Nakabayahi Yoshinobu, Misawa-Furihata Akiko, Tabata-Maruyama Hiroko, Iehara Tomoko, Sugimoto Tohru, Yamane Humitsugu, Yamasaki Masayuki, Shiwaku Kuninori, Yanagisawa Akio, Ono Megumi, Tokiwa Kazuaki, Iwai Naomi, Hashiba Mitsuoki, Abe Tatsuo, Sawada Tadashi

Abstract excerpt

Rhabdomyosarcoma is the most common soft tissue tumor seen in children and young adults, and it can be classified into 2 major histological subtypes, alveolar and embryonal. In the alveolar subtype, 2 recurrent chromosomal translocations, t(2;13)(q35;q14) and its variant t(1;13)(p36;q14), have been identified as the specific cytogenetic abnormalities. These translocations produce the PAX3-FOXO1 and PAX7-FOXO1...

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Share to Cytogenetic Analysis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oncogene Proteins, Fusion

Share to Paired Box Transcription Factors

Share to PAX3 Transcription Factor

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Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Rhabdomyosarcoma, Embryonal

Source

Identifiers

PMID: 19215790
DOI: 10.1016/j.cancergencyto.2008.10.016

Genes

PAX3
FOXO1
PAX7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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