Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation.

The New England journal of medicine - 12 Feb 2009

Hütter Gero, Nowak Daniel, Mossner Maximilian, Ganepola Susanne, Müssig Arne, Allers Kristina, Schneider Thomas, Hofmann Jörg, Kücherer Claudia, Blau Olga, Blau Igor W, Hofmann Wolf K, Thiel Eckhard

Abstract excerpt

Infection with the human immunodeficiency virus type 1 (HIV-1) requires the presence of a CD4 receptor and a chemokine receptor, principally chemokine receptor 5 (CCR5). Homozygosity for a 32-bp deletion in the CCR5 allele provides resistance against HIV-1 acquisition. We transplanted stem cells from a donor who was homozygous for CCR5 delta32 in a patient with acute myeloid leukemia and HIV-1 infection. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Retroviral Agents
Share to CD4 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD4 Lymphocyte Count

Share to CD4-Positive T-Lymphocytes

Share to Receptors, CCR5

Share to Stem Cell Transplantation

Share to Transplantation Chimera

Share to Transplantation, Homologous

Source

Identifiers

PMID: 19213682
DOI: 10.1056/NEJMoa0802905

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation.PMID 19213682Read ↗

Rapid Rebound of a Preexisting CXCR4-tropic Human Immunodeficiency Virus Variant After Allogeneic Transplantation With CCR5 Δ32 Homozygous Stem CellsSemantic proximity Read ↗

Legacy of a magic gene-CCR5-∆32: From discovery to clinical benefit in a generation.Semantic proximity Read ↗

Shift of HIV tropism in stem-cell transplantation with CCR5 Delta32 mutation.Semantic proximity Read ↗

Hematopoietic stem cell transplantation for HIV cure.Semantic proximity Read ↗

Sustained HIV-1 remission after heterozygous CCR5Δ32 stem cell transplantation.Semantic proximity Read ↗

CCR5-edited gene therapies for HIV cure: Closing the door to viral entry.Semantic proximity Read ↗

The prevalence of CCR5-Δ32 mutation in a cohort of Saudi stem cell donors.Semantic proximity Read ↗

Association of heterozygous CCR5Δ32 deletion with survival in HIV-infection: A cohort study.Semantic proximity Read ↗

Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids.Semantic proximity Read ↗

Cord blood transplantation for cure of HIV infections.Semantic proximity Read ↗

Knowledge From London and Berlin: Finding Threads to a Functional HIV Cure.Semantic proximity Read ↗

CCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.