Article
HLA-B*2709 and lack of susceptibility to sacroiliitis: further support from the clinic.
Clinical and experimental rheumatology - 1 Jan 2000
Cauli A, Vacca A, Dessole G, Fiorillo M T, Porru G, Ibba V, Mura V, Piga M, Sorrentino R, Mathieu A
Abstract excerpt
Interferons (IFN) are well known triggers of immunomediated diseases in genetically predisposed subjects. We describe the unique case of a HLA-B*2709 positive subject who underwent IFN-alpha treatment for essential thrombocythemia and developed arthritis of the proximal interphalangeal joints of the hands but not sacroiliitis. The possible mechanisms of IFN-induced arthritis are discussed.
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