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Article

Tropomyosins in skeletal muscle diseases.

Advances in experimental medicine and biology - 1 Jan 2008

Kee Anthony J, Hardeman Edna C

Abstract excerpt

A number of congenital muscle diseases and disorders are caused by mutations in genes that encode the proteins present in or associated with the thin filaments of the muscle sarcomere. These genes include alpha-skeletal actin (ACTA1), beta-tropomyosin (TPM2), alpha-tropomyosin slow (TPM3), nebulin (NEB), troponin I fast (TNNI2), troponin T slow (TNNT1), troponin T fast (TNNT3) and cofilin (CFL2). Mutations in two...

Topics

Actins
Animals
Cytoskeleton
Genotype
Humans
Mice
Models, Biological
Models, Genetic
Muscle, Skeletal
Muscles
Muscular Diseases
Mutation
Protein Isoforms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sarcomeres

Tropomyosin

Source

Identifiers

PMID: 19209820
DOI: 10.1007/978-0-387-85766-4_12

Genes

TPM2
TPM3
ACTA1
CFL2
NEB
TNNI2
TNNT1
TNNT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Tropomyosins in skeletal muscle diseases.PMID 19209820Read ↗

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