Article
Contrasting clinical manifestations of SDHB and VHL associated chromaffin tumours.
Endocrine-related cancer - 1 Jun 2009
Srirangalingam Umasuthan, Khoo Bernard, Walker Lisa, MacDonald Fiona, Skelly Robert H, George Emad, Spooner David, Johnston Linda B, Monson John P, Grossman Ashley B, Drake W M, Akker Scott A, Pollard Patrick J, Plowman Nick, Avril Norbert, Berney Daniel M, Burrin Jacky M, Reznek Rodney H, Kumar V K Ajith, Maher Eamonn R, Chew Shern L
Abstract excerpt
Mutations in succinate dehydrogense-B (SDHB) and the von Hippel-Lindau (VHL) genes result in an increased risk of developing chromaffin tumours via a common aetiological pathway. The aim of the present retrospective study was to compare the clinical phenotypes of disease in subjects developing chromaffin tumours as a result of SDHB mutations or VHL disease. Thirty-one subjects with chromaffin tumours were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.