Article
The occurrence of SDHB gene mutations in pheochromocytoma.
Annals of the New York Academy of Sciences - 1 Aug 2006
Van Nederveen Francien H, Dinjens Winand N M, Korpershoek Esther, De Krijger Ronald R
Abstract excerpt
Pheochromocytomas (PCCs) are rare tumors arising from neural crest-derived chromaffin cells. The majority of these tumors are located in the adrenals and gives rise to catecholamine overproduction. In at least 10% of the cases the tumors are located outside the adrenal gland, in extra-adrenal sites like the bladder and the organ of Zuckerkandl. Recent investigations have found mutations in succinate dehydrogenase...
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