Article
Immunogenicity of allogeneic adipose-derived stem cells in a rat spinal fusion model.
Tissue engineering. Part A - 1 Sept 2009
McIntosh Kevin R, Lopez Mandi J, Borneman Jade N, Spencer Nakia D, Anderson Paul A, Gimble Jeffrey M
Abstract excerpt
Adipose-derived stem cells (ASCs) express a nonimmunogenic profile as shown by in vitro studies that demonstrate a lack of T cell proliferation to allogeneic ASCs as well as ASC-mediated suppression of mixed lymphocyte reactions. To determine whether these observations would translate in vivo, im...
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