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Article

Comparison of Human Mesenchymal Stem Cells Derived From Adipose Tissue and Bone Marrow for Ex Vivo Gene Therapy in Rat Spinal Fusion Model

1 Apr 2008

Abstract excerpt

STUDY DESIGN: Rat spinal fusion model. OBJECTIVE: To compare the efficacy of human adipose tissue-derived mesenchymal stem cells (HATDMSCs) and human bone marrow-derived mesenchymal stem cells (HBMDMSCs) transduced with an adenovirus containing the cDNA for bone morphogenetic proteins (BMP)-2 for inducing spinal fusion in an athymic rat model. SUMMARY OF BACKGROUND DATA: Recombinant BMPs have successfully induced...

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PMID: 18404105
DOI: 10.1097/brs.0b013e31816b45c3

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