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Article

Expression of epigenetic effectors in decidualizing human endometrial stromal cells

7 May 2012

Abstract excerpt

Cyclic differentiation of human endometrial stromal cells (HESCs) into decidual cells is a highly coordinated process essential for embryo implantation and pregnancy. This differentiation process is closely recapitulated in culture upon exposure of purified HESCs to cyclic AMP and progesterone signaling. Mining of gene expression data revealed that HESCs express 147 genes coding for epigenetic effectors, 33 (22%)...

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PMID: 22570358
DOI: 10.1093/molehr/gas020

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