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Article

The influence of menstrual cycle and endometriosis on endometrial methylome

11 Jan 2016

Abstract excerpt

BACKGROUND: Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes, and the menstrual cycle phase-dependent epigenetic signature should be considered when studying endometrial disorders. So far, no studies have been performed to evaluate the...

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PMID: 26759613
DOI: 10.1186/s13148-015-0168-z

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