Article
The molecular basis of genetic lipodystrophies.
Clinical biochemistry - 1 May 2002
Bhayana Shelly, Hegele Robert A
Abstract excerpt
OBJECTIVES: Hyperinsulinemia is often associated with a cluster of metabolic abnormalities, which usually presents before the onset of frank diabetes. Lipodystrophy syndromes are frequently associated with hyperinsulinemia and may act as models for insulin resistance. Lipodystrophy is characterized in broad terms by loss of subcutaneous adipose tissue. Despite heterogeneous causes, which include both genetic and...
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