[Methods of study on cytochrome P450 in relation to the metabolism and toxicity of alcohol and drugs].

Article

[Methods of study on cytochrome P450 in relation to the metabolism and toxicity of alcohol and drugs].

Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence - 1 Jun 1998

Nakajima T

Abstract excerpt

Metabolism of xenobiotics such as alcohol and organic solvents can be divided roughly into two types: functional and conjugation reactions. Cytochrome P450 (CYP) is the primary group of enzymes involved in the former. Therefore, CYP analysis is essential for the study of the metabolism and toxici...

Topics

Alcohols
Animals
Animals, Genetically Modified
Blotting, Western
Cytochrome P-450 CYP2E1
Cytochrome P-450 Enzyme System
DNA
Genotype
Humans
Polymerase Chain Reaction
Solvents
Toluene

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