Article
Joint effect of obesity and TNFA variability on asthma: two international cohort studies.
The European respiratory journal - 1 May 2009
Castro-Giner F, Kogevinas M, Imboden M, de Cid R, Jarvis D, Mächler M, Berger W, Burney P, Franklin K A, Gonzalez J R, Heinrich J, Janson C, Omenaas E, Pin I, Rochat T, Sunyer J, Wjst M, Antó J-M, Estivill X, Probst-Hensch N M
Abstract excerpt
Obesity is a risk factor for asthma. Adipose tissue expresses pro-inflammatory molecules including tumour necrosis factor (TNF), and levels of TNF are also related to polymorphisms in the TNF-alpha (TNFA) gene. The current authors examined the joint effect of obesity and TNFA variability on asthm...
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