Article
IP-10 correlates with hepatitis C viral load, hepatic inflammation and fibrosis and predicts hepatitis C virus relapse or non-response in HIV-HCV coinfection.
Antiviral therapy - 1 Jan 2008
Reiberger Thomas, Aberle Judith H, Kundi Michael, Kohrgruber Norbert, Rieger Armin, Gangl Alfred, Holzmann Heidemarie, Peck-Radosavljevic Markus
Abstract excerpt
BACKGROUND: Interferon (IFN)-gamma inducible protein 10 (IP-10) is increased in hepatitis C virus (HCV) monoinfection, correlates with hepatic inflammation and predicts non-response (NR) to antiviral therapy. We aimed to clarify the role of IP-10 in HIV-HCV coinfection. METHODS: Serum IP-10 levels of 30 HIV-HCV-coinfected patients treated with pegylated (PEG)-IFN-alpha2a (180 microg/week) and ribavirin (800-1,200...
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