Article
The PCSK9 gene E670G polymorphism affects low-density lipoprotein cholesterol levels but is not a risk factor for coronary artery disease in ethnic Chinese in Taiwan.
Clinical chemistry and laboratory medicine - 1 Jan 2009
Hsu Lung-An, Teng Ming-Sheng, Ko Yu-Lin, Chang Chi-Jen, Wu Semon, Wang Chun-Li, Hu Chiao-Feng
Abstract excerpt
BACKGROUND: An E670G polymorphism of the exon 12 of the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene was recently found to be associated with increased plasma low-density lipoprotein cholesterol (LDL-C) levels and severity of coronary atherosclerosis. This case-control study tested for a possible link between this PCSK9 polymorphism and the risk of coronary artery disease (CAD) in an ethnic Chinese...
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