Article
Sweet liking phenotype, alcohol craving and response to naltrexone treatment in alcohol dependence.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Garbutt James C, Osborne Michael, Gallop Robert, Barkenbus John, Grace Kathy, Cody Meghan, Flannery Barbara, Kampov-Polevoy Alexey B
Abstract excerpt
AIMS: To investigate the relationship between the sweet liking/sweet disliking phenotype (a putative probe of brain opioid function), craving for alcohol and response to treatment with naltrexone in individuals with alcohol dependence. METHODS: Forty individuals with alcohol dependence were enrolled in a 12-week open-label study of 50 mg of naltrexone with four sessions of motivational enhancement therapy. Prior...
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