Article
Telomere length maintenance--an ALTernative mechanism.
Cytogenetic and genome research - 1 Jan 2008
Royle N J, Foxon J, Jeyapalan J N, Mendez-Bermudez A, Novo C L, Williams J, Cotton V E
Abstract excerpt
The Alternative Lengthening of Telomeres (ALT) mechanism is utilised by approximately 10% of human tumours and a higher proportion of some types of sarcomas. ALT+ cell lines and tumours show heterogeneous telomere length, extra-chromosomal circular and linear telomeric DNA, ALT associated promyel...
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