Article
Dissecting the non-canonical functions of telomerase.
Cytogenetic and genome research - 1 Jan 2008
Parkinson E K, Fitchett C, Cereser B
Abstract excerpt
It is now well established that the canonical function of telomerase protects the telomere repeats from erosion and the consequent induction of replicative senescence or apoptosis. In the absence of key cell cycle checkpoint proteins, the canonical function of telomerase also prevents chromosome fusions and immortalizes human cells. The canonical function of telomerase requires both the telomerase reverse...
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