Article
Protective role of 27bp repeat polymorphism in intron 4 of eNOS gene in lacunar infarction.
Free radical research - 1 Mar 2009
Yemişçi Müge, Sinici Incilay, Ozkara H Asuman, Hayran Mutlu, Ay Hakan, Celtikçi Basak, Onder Evren, Büyükşerbetci Gülseren, Kaya E Baris, Tokgözoglu Lale, Dalkara Turgay
Abstract excerpt
Association of the three potential endothelial nitric oxide synthase gene (eNOS) polymorphisms (T-786C in promoter region, G894T in exon 7 and tandem 27-bp repeats in intron 4) with an increased risk of lacunar infarction (LI) were investigated. Genotypes of 70 patients and 81 healthy controls were determined through PCR with or without RFLP. Flow-mediated dilatation (FMD) was performed to assess...
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