Article
Human antimicrobial protein hCAP18/LL-37 promotes a metastatic phenotype in breast cancer.
Breast cancer research : BCR - 1 Jan 2009
Weber Günther, Chamorro Clara Ibel, Granath Fredrik, Liljegren Annelie, Zreika Sami, Saidak Zuzana, Sandstedt Bengt, Rotstein Samuel, Mentaverri Romuald, Sánchez Fabio, Pivarcsi Andor, Ståhle Mona
Abstract excerpt
INTRODUCTION: Human cathelicidin antimicrobial protein, hCAP18, and its C-terminal peptide LL-37 is a multifunctional protein. In addition to being important in antimicrobial defense, it induces chemotaxis, stimulates angiogenesis and promotes tissue repair. We previously showed that human breast...
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