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Article

Human antimicrobial protein hCAP18/LL-37 promotes a metastatic phenotype in breast cancer.

Breast cancer research : BCR - 1 Jan 2009

Weber Günther, Chamorro Clara Ibel, Granath Fredrik, Liljegren Annelie, Zreika Sami, Saidak Zuzana, Sandstedt Bengt, Rotstein Samuel, Mentaverri Romuald, Sánchez Fabio, Pivarcsi Andor, Ståhle Mona

Abstract excerpt

INTRODUCTION: Human cathelicidin antimicrobial protein, hCAP18, and its C-terminal peptide LL-37 is a multifunctional protein. In addition to being important in antimicrobial defense, it induces chemotaxis, stimulates angiogenesis and promotes tissue repair. We previously showed that human breast cancer cells express high amounts of hCAP18, and hypothesised that hCAP18/LL-37 may be involved in tumour progression....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19183447
DOI: 10.1186/bcr2221
PMCID: PMC2687709

Genes

ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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