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Article

Mycoplasmal lipoprotein p37 binds human protein HER2.

Microbiological research - 1 Nov 2016

Wu Jun, Wu Lijuan, Fang Cheng, Nie Rong, Wang Jiamou, Wang Xuan, Liu Wenbin

Abstract excerpt

Mycoplasmas are a group of microbes that can cause human diseases. The mycoplasmal lipoprotein p37 promotes cancer metastasis, at least in part, by interacting with EGFR. In this study, we show that the p37 lipoprotein binds another member of the EGFR family, HER2, through the HER2 extracellular domain. The binding of p37-HER2 promotes phosphorylation of HER2 and activates the downstream signaling molecule...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27664744
DOI: 10.1016/j.micres.2016.08.003

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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