Article
Lung function in 30-year-old alpha-1-antitrypsin-deficient individuals.
Respiratory medicine - 1 Jun 2009
Bernspång Elisabeth, Wollmer Per, Sveger Tomas, Piitulainen Eeva
Abstract excerpt
BACKGROUND: Alpha-1-antitrypsin (AAT) deficiency increases the risk of emphysema, especially in smokers. In 1972-1974, all 200,000 Swedish new-born infants were screened for AAT deficiency and individuals with severe (PiZZ) and moderate (PiSZ) deficiency have been followed-up regularly. The aim of the present study was to examine their lung function at the age of 30 years, comparing them to a group of age-matched...
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