Article
Intron polymorphism in the KIAA0350 gene is reproducibly associated with susceptibility to type 1 diabetes (T1D) in the Han Chinese population.
Clinical endocrinology - 1 Jul 2009
Wu Xiaopan, Zhu Xilin, Wang Xin, Ma Juan, Zhu Shuying, Li Jingyun, Liu Ying
Abstract excerpt
OBJECTIVE: Three independent genome-wide association studies in white populations have reported that single nucleotide polymorphisms (SNPs) in the KIAA0350 gene are associated with susceptibility to type 1 diabetes (T1D). The gene product of KIAA0350 is predicted to be a sugar binding C-type lectin. In the present study, we investigated whether SNPs in this gene were associated with T1D in the Han Chinese...
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