Article
[Determining drug resistance of the clinical strains of Mycobacterium tuberculosis to pyrazinamide].
Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Jan 2008
Nizova A V, Stepanshina V N, Maĭskaia N V, Mironova R I, Bogun A G, Domotenko L V, Morozova T P, Shemiakin I G
Abstract excerpt
Description of the pyrazinamide-resistant clinical strains of M. tuberculosis derived from sputum of patients treated in TB clinics in Tula was made (June, 2001 - July, 2002). It was demonstrated that 30.3% (n = 91) strains were resistant to pyrazinamide. It was found out that these strains were resistant to other antituberculosis drugs in most cases. The method of PCR-sequencing was used to find the mutations in...
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