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Article

Novel mutations in Thai patients with glanzmann thrombasthenia.

European journal of haematology - 1 Dec 2017

Ittiwut Rungnapa, Suchartlikitwong Pintip, Kittikalayawong Yaowaree, Ittiwut Chupong, Prasopsanti Karan, Sosothikul Darintr, Shotelersuk Vorasuk, Suphapeetiporn Kanya

Abstract excerpt

OBJECTIVES: Glanzmann thrombasthenia (GT) is an autosomal recessive platelet disorder, caused by defects of the platelet integrin αIIbβ3 (GPIIb/IIIa) resulting from pathogenic mutations in either ITGA2B or ITGB3. It is characterized by spontaneous mucocutaneous bleeding. The molecular features of GT in Thailand have not been identified. This study aimed to determine the clinical and molecular features of...

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PMID: 28888044
DOI: 10.1111/ejh.12965

Genes

ITGB3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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