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Article

Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis.

Journal of bone and mineral metabolism - 1 Jan 2009

Mori Seijiro, Kou Ikuyo, Sato Hidenori, Emi Mitsuru, Ito Hideki, Hosoi Takayuki, Ikegawa Shiro

Abstract excerpt

Osteoporosis is a multi-factorial common disease, which is caused by combination of genetic as well as environmental factors. Among several factors, osteoclast acidification pathways during bone resorption might play an important role. Carbonic anhydrases, consisting of a gene family, are essential for pH regulation by the osteoclast. Clinically, use of carbonic anhydrase inhibitors has been known to be...

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PMID: 19172221
DOI: 10.1007/s00774-008-0031-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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