Article
Use of the nuc1 null mutant for analysis of yeast mitochondrial nucleoids.
The Journal of general and applied microbiology - 1 Dec 2008
Miyakawa Isamu, Fujimura Ryoko, Kadowaki Yu
Abstract excerpt
Mitochondrial DNA (mtDNA) of the yeast Saccharomyces cerevisiae is organized to form mitochondrial nucleoids (mt-nucleoids) by association with specific proteins. The sensitivity of DNA-protein complexes to nuclease digestion is a useful means for examining DNA packaging and organization. However, the mt-nucleoids isolated from wild-type cells of S. cerevisiae demonstrated a significant amount of endogenous...
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