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Article

Staphylococcus aureus as an intracellular pathogen: the role of small colony variants.

Trends in microbiology - 1 Feb 2009

Sendi Parham, Proctor Richard A

Abstract excerpt

Increasing evidence indicates that Staphylococcus aureus might be a facultative intracellular pathogen. In particular, certain subpopulations, called small colony variants (SCVs), seem to be well adapted to the intracellular milieu. When compared to 'normal' staphylococcal strains, SCVs show increased uptake by host cells, resistance to intracellular defenses and reduced stimulation of host defenses. We propose...

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PMID: 19162480
DOI: 10.1016/j.tim.2008.11.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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