Article
Haplotypes of the NR4A2/NURR1 gene and cardiovascular disease: the Rotterdam Study.
Human mutation - 1 Mar 2009
Kardys Isabella, van Tiel Claudia M, de Vries Carlie J M, Pannekoek Hans, Uitterlinden André G, Hofman Albert, Witteman Jacqueline C M, de Maat Moniek P M
Abstract excerpt
Nuclear receptor subfamily 4, group A, member 2 (NR4A2, also called Nurr1) has lately become of interest with regard to atherogenesis. We examined the association between common variation in the NR4A2 gene and cardiovascular disease in the Rotterdam Study, a prospective population-based study among persons aged > or = 55 years. Three SNPs that tag common haplotypes across a 36-kb region surrounding the NR4A2 gene...
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