Article
Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.
European journal of human genetics : EJHG - 1 Jul 2009
Need Anna C, Keefe Richard S E, Ge Dongliang, Grossman Iris, Dickson Sam, McEvoy Joseph P, Goldstein David B
Abstract excerpt
The Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Phase 1 Schizophrenia trial compared the effectiveness of one typical and four atypical antipsychotic medications. Although trials such as CATIE present important opportunities for pharmacogenetics research, the very richness of the clinical data presents challenges for statistical interpretation, and in particular the risk that data mining...
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