Patterns of Gene-Specific and Total Transcriptional Activity during the<i>Plasmodium falciparum</i>Intraerythrocytic Developmental Cycle

Abstract excerpt

The relationships among gene regulatory mechanisms in the malaria parasite Plasmodium falciparum throughout its asexual intraerythrocytic developmental cycle (IDC) remain poorly understood. To investigate the level and nature of transcriptional activity and its role in controlling gene expression during the IDC, we performed nuclear run-on on whole-transcriptome samples from time points throughout the IDC and...

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