Plasmodium Falciparum Regulates Transcriptional Output by Modulating The Activity of RNA Polymerase II Rather Than Its Recruitment

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>The asexual phase of the unicellular eukaryotic parasite <italic>Plasmodium falciparum</italic> takes place in the human red blood cell (RBC). During the 48 h between RBC infection and the release of new progeny – the intraerythrocytic developmental cycle (IDC) – transcripts levels for most of the parasite’s ~5,772 genes are set by the integration of transcriptio...

Topics

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• HIV Research and Treatment
• Invertebrate Immune Response Mechanisms
• Malaria Research and Control
• Mosquito-borne diseases and control
• RNA and protein synthesis mechanisms
• Sperm and Testicular Function
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

715e5872-4551-5570-a6b9-57a06b730394

DOI

10.21203/rs.3.rs-74869/v1