Article
Stability improvement of the fatty acid binding protein Sm14 from S. mansoni by Cys replacement: structural and functional characterization of a vaccine candidate.
Biochimica et biophysica acta - 1 Apr 2009
Ramos Celso R R, Spisni Alberto, Oyama Sérgio, Sforça Mauricio L, Ramos Henrique R, Vilar Mônica M, Alves Adriana C, Figueredo Rita C R, Tendler Míriam, Zanchin Nilson I T, Pertinhez Thelma A, Ho Paulo Lee
Abstract excerpt
The Schistosoma mansoni fatty acid binding protein (FABP), Sm14, is a vaccine candidate against, S. mansoni and F. hepatica. Previously, we demonstrated the importance of a correct fold to achieve protection in immunized animals after cercariae challenge [[10]. C.R.R. Ramos, R.C.R. Figueredo, T.A...
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