Article
Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in women.
BMC medical genetics - 17 Jan 2009
Song Yiqing, Hsu Yi-Hsiang, Niu Tianhua, Manson Joann E, Buring Julie E, Liu Simin
Abstract excerpt
BACKGROUND: Ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7) play a central role in magnesium homeostasis, which is critical for maintaining glucose and insulin metabolism. However, it is unclear whether common genetic variation in TRPM6 and TRPM7 contributes to risk of type 2 diabetes. METHODS: We conducted a nested case-control study in the Women's Health Study. During a...
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