Article
Delta-crystallin enhancer binding factor 1 controls the epithelial to mesenchymal transition phenotype and resistance to the epidermal growth factor receptor inhibitor erlotinib in human head and neck squamous cell carcinoma lines.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2009
Haddad Yasmine, Choi Woonyoung, McConkey David J
Abstract excerpt
PURPOSE: Although the epidermal growth factor receptor (EGFR) is overexpressed in a majority of head and neck squamous cell carcinomas (HNSCC), only a minority of patients derive substantial clinical benefit from EGFR inhibitors. We initiated the present study to identify the mechanisms underlyin...
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