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Regulation of Prostaglandin Transporters in Colorectal Neoplasia

19 Mar 2008

Abstract excerpt

Prostaglandin E(2) (PGE(2)) promotes cancer progression by affecting cell proliferation, apoptosis, angiogenesis, and the immune response. It has been reported that PGE(2) is transported or passes through the cell membrane via prostaglandin-specific transporters including the prostaglandin transporter (PGT, an influx transporter) and the multidrug resistance-associated protein 4 (an efflux transporter). PGT can...

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PMID: 19138942
DOI: 10.1158/1940-6207.capr-07-0009

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