Article
Molecular and genetic mechanisms in melanoma.
Collegium antropologicum - 1 Oct 2008
Gruber Franjo, Kastelan Marija, Brajac Ines, Saftić Marina, Peharda Vesna, Cabrijan Leo, Stanić Zgombić Zrinka, Simonić Edita
Abstract excerpt
Recent studies have indicated an increasing incidence of melanoma worldwide. Although UV signature mutations are found rarely in melanoma cells, there is some evidence that intense intermittent exposure to sunlight can induce melanocyte tumorigenesis, and this is also observed after UV irradiation in some animals. The purpose of this paper is to review some of the most important mechanisms involved in the...
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