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Article

Deciphering complex mechanisms in neurodegenerative diseases: the advent of systems biology.

Trends in neurosciences - 1 Feb 2009

Noorbakhsh Farshid, Overall Christopher M, Power Christopher

Abstract excerpt

Classical biological methods involving analyses of one or several genes have been the mainstay for studying the pathogenesis of neurodegenerative disorders. However, it has become clear that these diseases exhibit complex molecular interactions involving both host genomes and environmental determinants. Systems biology represents an integrated and deeper investigation of interacting biomolecules within cells or...

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PMID: 19135729
DOI: 10.1016/j.tins.2008.10.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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