Article
High long-term absolute risk of recurrent venous thromboembolism in patients with hereditary deficiencies of protein S, protein C or antithrombin.
Thrombosis and haemostasis - 1 Jan 2009
Brouwer Jan-Leendert P, Lijfering Willem M, Ten Kate Min Ki, Kluin-Nelemans Hanneke C, Veeger Nic J G M, van der Meer Jan
Abstract excerpt
Hereditary deficiencies of protein S, protein C and antithrombin are known risk factors for first venous thromboembolism. We assessed the absolute risk of recurrence, and the contribution of concomitant thrombophilic defects in a large cohort of families with these deficiencies. Annual incidence of recurrence was estimated in 130 deficient patients, with separate estimates for those with each of protein S,...
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