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Article

Risk of recurrent venous thrombosis in homozygous carriers and double heterozygous carriers of factor V Leiden and prothrombin G20210A.

Circulation - 20 Apr 2010

Lijfering Willem M, Middeldorp Saskia, Veeger Nic J G M, Hamulyák Karly, Prins Martin H, Büller Harry R, van der Meer Jan

Abstract excerpt

BACKGROUND: Homozygous or double heterozygous factor V Leiden and/or prothrombin G20210A is a rare inherited thrombophilic trait. Whether individuals with this genetic background have an increased risk of recurrent venous thrombosis is uncertain. METHODS AND RESULTS: A case-control design within a large cohort of families with thrombophilia was chosen to calculate the risk of recurrent venous thrombosis in...

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PMID: 20368522
DOI: 10.1161/CIRCULATIONAHA.109.906347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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