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The risk of recurrent venous thromboembolism in patients with inherited deficiency of natural anticoagulants antithrombin, protein C and protein S.

Haematologica - 1 May 2006

De Stefano Valerio, Simioni Paolo, Rossi Elena, Tormene Daniela, Za Tommaso, Pagnan Antonio, Leone Giuseppe

Abstract excerpt

Few data are available on the risk of recurrent venous thromboembolism (VTE) associated with the rare inherited deficiencies of natural anticoagulants. We studied 602 patients with previous VTE: the incidence of first recurrence in the absence of anticoagulation was retrospectively estimated in 64 patients with deficiency of antithrombin (AT, n=14), protein C (PC, n=28), or protein S (PS, n=22) and 538 with no...

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PMID: 16670075

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