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Article

Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: results from a randomized trial.

Blood - 1 Dec 2008

Kearon Clive, Julian Jim A, Kovacs Michael J, Anderson David R, Wells Philip, Mackinnon Betsy, Weitz Jeffrey I, Crowther Mark A, Dolan Sean, Turpie Alexander G, Geerts William, Solymoss Susan, van Nguyen Paul, Demers Christine, Kahn Susan R, Kassis Jeannine, Rodger Marc, Hambleton Julie, Gent Michael, Ginsberg Jeffrey S

Abstract excerpt

We sought to determine whether thrombophilic defects increase recurrent venous thromboembolism (VTE) during warfarin therapy. Six hundred sixty-one patients with unprovoked VTE who were randomized to extended low-intensity (international normalized ratio [INR], 1.5-1.9) or conventional-intensity (INR, 2.0-3.0) anticoagulant therapy were tested for thrombophilia and followed for a mean of 2.3 years. One or more...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18791166
DOI: 10.1182/blood-2008-06-163279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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