Article
Positive association of neuroligin-4 gene with nonspecific mental retardation in the Qinba Mountains Region of China.
Psychiatric genetics - 1 Feb 2009
Qi Hongbin, Xing Lianxi, Zhang Kejin, Gao Xiaocai, Zheng Zijian, Huang Shaoping, Guo Yale, Zhang Fuchang
Abstract excerpt
OBJECTIVE: Neuroligin-4 is essential for proper brain function. Some studies indicate a close relationship between neuroligin-4 and several human psychiatric conditions. METHODS: The case-control method was used to study the association between nonspecific mental retardation (NSMR) and genetic variants of neuroligin-4 gene (NLGN4). Five single nucleotide polymorphisms (SNPs: rs5916271, rs7049300, rs6638575,...
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