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Neuronal migration disorders: clinical, neuroradiologic and genetics aspects

18 Dec 2008

Abstract excerpt

UNLABELLED: Disorders of neuronal migration are a heterogeneous group of disorders of nervous system development. One of the most frequent disorders is lissencephaly, characterized by a paucity of normal gyri and sulci resulting in a 'smooth brain'. There are two pathologic subtypes: classical and cobblestone. Six different genes could be responsible for this entity (LIS1, DCX, TUBA1A, VLDLR, ARX, RELN), although...

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PMID: 19120042
DOI: 10.1111/j.1651-2227.2008.01160.x

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