Polyamine as a signaling molecule for controlling an adaptive mutation.

Abstract excerpt

In the absence of exogenous polyamines, the polyamine-deficient Escherichia coli mutant shows not only a characteristic dual-phase growth with abnormal growth, growth arrest, and normal growth after mutation, but also a higher expression of the SOS genes than the polyamine-proficient wild type. The interval of the growth arrest is inversely regulated in a polyamine concentration-dependent manner. These results...

Topics

• Escherichia coli
• Escherichia coli Proteins
• Gene Expression Regulation, Bacterial
• Mutation
• Polyamines
• SOS Response, Genetics
• Signal Transduction