Article
Polyamines and glutamate decarboxylase-based acid resistance in Escherichia coli.
The Journal of biological chemistry - 20 Jun 2003
Jung Il Lae, Kim In Gyu
Abstract excerpt
The expression of gadA and gadB, which encode two glutamate decarboxylases (GADs) of Escherichia coli, is induced by an acidic environment and participate in acid resistance. In this study, we constructed a polyamine-deficient mutant and investigated the role of polyamines in acid resistance. The expression of gadA and gadB was shown to be dependent on polyamines. For that reason, the polyamine-deficient mutant...
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