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Article

Histone Deacetylase 8 in Neuroblastoma Tumorigenesis

31 Dec 2008

Abstract excerpt

PURPOSE: The effects of pan-histone deacetylase (HDAC) inhibitors on cancer cells have shown that HDACs are involved in fundamental tumor biological processes such as cell cycle control, differentiation, and apoptosis. However, because of the unselective nature of these compounds, little is known about the contribution of individual HDAC family members to tumorigenesis and progression. The purpose of this study...

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PMID: 19118036
DOI: 10.1158/1078-0432.ccr-08-0684

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