Article
Transcription factor 8 activates R-Ras to regulate angiogenesis.
Biochemical and biophysical research communications - 6 Feb 2009
Inuzuka Takayuki, Tsuda Masumi, Kawaguchi Hideaki, Ohba Yusuke
Abstract excerpt
We have recently reported that transcription factor 8 (TCF8) negatively regulates pathological angiogenesis by regulating endothelial invasiveness by acting as a transcriptional attenuator of matrix metalloproteinase 1. TCF8 also modulates cell-matrix and cell-cell adhesion; however molecular mec...
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